Cycle 2 – Module 2 – Lecture 3 – DHEA Diagnosis (2h12)

This is an interesting video, which shows that in young adults, DHEA is secreted in equivalent amounts as cortisol and functions as a protector against any excessive catabolic action of cortisol. The session reviews the actions, productions, and high serum levels of DHEA (sulfate).

With age, there is a rapid, progressive decline in the hypothalamo-pituitary- adrenal-DHEA axis resulting in an increasingly greater DHEA deficiency.

The diagnosis of DHEA deficiency is based on questionnaires and an interview on psychological and physical complaints, diseases that can be facilitated by DHEA deficiency, and laboratory tests.

An overview of the scientific studies that show various diseases to be associated with low DHEA levels from lipid disorders to atherosclerosis, arterial and pulmonary hypertension, coronary heart disease myocardial infarction, heart failure, metabolic syndrome, obesity, type 2 diabetes, arthritis, lupus, osteopenia, inflammation, virus infections, bacterial and parasite infections, cancer, Alzheimer’s diseases, higher mortality, and several other disorders.

The physical signs of DHEA deficiency at puberty, in early and late adulthood at the level of the skin, eyes, muscles, joints, body hair of armpits and pubic area, abdomen, are shown here.

Special attention is provided on which laboratory tests to request: serum, saliva, 24-hour urine, and on how to interpret them in the function of the studies that show low serum DHEA sulfate tests within the reference range to be linked to disease.

This course is composed of 1 video, 1 PDF presentation, 1 PDF with the references, and 1 quiz.

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  • Reference: M9_L2-1-1-4-11.
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